The Function and Modulation of Brain Cells During Sensory Processing

Grant number: 1063533 | Funding period: 2014 - 2018

Completed

Abstract

Understanding how brain cells translate sensory input into behaviour is central to explaining how the brain works. My research focuses on the long-standing question of how information from different brain regions is received and processed within individual brain cells. This research is crucial to understanding brain function and can provide a greater understanding of the neuronal processes underlying diseases such as epilepsy, schizophrenia, depression and alcoholism.

Related publications (10)

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A thalamocortical pathway controlling impulsive behavior

R Guzulaitis, LM Palmer

2023-12-01

Planning and anticipating motor actions enables movements to be quickly and accurately executed. However, if anticipation is not p..

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Neural basis of anticipation and premature impulsive action in the frontal cortex

R Guzulaitis, L Godenzini, LM Palmer

2022-12-01

Planning motor actions can improve behavioral performance; however, it can also lead to premature actions. Although the anterior l..

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Dendritic Mechanisms for In Vivo Neural Computations and Behavior

L Fischer, RM Soto-Albors, VD Tang, B Bicknell, C Grienberger, V Francioni, R Naud, LM Palmer, N Takahashi

2022-11-09

Dendrites receive the vast majority of a single neuron’s inputs, and coordinate the transformation of these signals into neuronal ..

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Dendritic Compartmentalization of Learning-Related Plasticity

L Godenzini, AS Shai, LM Palmer

2022-05-01

The dendrites of cortical pyramidal neurons receive synaptic inputs from different pathways that are organized according to their ..

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The role of higher-order thalamus during learning and correct performance in goal-directed behavior

D La Terra, AS Bjerre, M Rosier, R Masuda, TJ Ryan, LM Palmer

2022-03-01

The thalamus is a gateway to the cortex. Cortical encoding of complex behavior can therefore only be understood by considering the..

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Auditory input enhances somatosensory encoding and tactile goal-directed behavior

L Godenzini, D Alwis, R Guzulaitis, S Honnuraiah, GJ Stuart, LM Palmer

2021-12-01

The capacity of the brain to encode multiple types of sensory input is key to survival. Yet, how neurons integrate information fro..

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Probing Cortical Activity During Head-Fixed Behavior

AS Bjerre, LM Palmer

2020-02-28

The cortex is crucial for many behaviors, ranging from sensory-based behaviors to working memory and social behaviors. To gain an ..

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A reward-based behavioral platform to measure neural activity during head-fixed behavior

AH Micallef, N Takahashi, ME Larkum, LM Palmer

2017-05-31

Understanding the neural computations that contribute to behavior requires recording from neurons while an animal is behaving. Thi..

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Transcranial magnetic stimulation (TMS) inhibits cortical dendrites

SC Murphy, LM Palmer, T Nyffeler, RM Müri, ME Larkum

2016-03-18

One of the leading approaches to non-invasively treat a variety of brain disorders is transcranial magnetic stimulation (TMS). How..

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Dendrites: Recording from fine neuronal structures using patch-clamp and imaging techniques

S Gasparini, LM Palmer

2016-01-01

Dendrites are the principal site of synaptic input onto neurons but despite their importance in neuronal signaling, little is know..

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